Clinicopathological findings in persistent corneal cowpox infection.

ing improved outcomes. The result of longer healing times in fungal ulcers may be influenced by this. Re-epithelialization is a difficult endpoint tomeasure, particularly in fungal keratitis, so this result should be interpreted with some caution. Other factors associated with fungal and bacterial keratitis cases, such as geographic location of the patients, could act as confounders in this study. Selection bias could occur because use of topical antibiotics prior to presentation is more common than antifungal use, and culture-negative bacterial ulcers may be milder. However, the results of this study suggest that fungal keratitis has a higher risk of perforation and may have worse overall outcomes compared with bacterial keratitis.